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Features & Benefits
Hydroxo B12 with Folinic Acid is a methyl-free vitamin B12 and folate supplement designed to support healthy methylation, energy production, cognition, cardiovascular function, detoxification pathways, and homocysteine balance. It combines hydroxocobalamin (a non-methylated form of B12) with folinic acid (a non-methylated form of folate) in a cherry-flavored lozenge for enhanced absorption and ease of use.
This formula is intended for individuals who may be sensitive to methylated nutrients such as methylcobalamin or methylfolate, while still supporting the body’s natural methylation pathways.
The product is commonly used to support:
- Healthy methylation
- Energy production
- Cognitive and neurological function
- Detoxification pathways
- Healthy homocysteine levels
- Cardiovascular health
- DNA/RNA synthesis
- Red blood cell formation
- Mood and mental clarity
Dose & Administration
Suggested Use
- Take 1 lozenge daily or as directed by a healthcare professional
- Lozenge may be broken into smaller pieces if a lower dose is desired
- Allow lozenge to dissolve slowly in the mouth before swallowing
- Do not take within 5 hours of bedtime, as it may interfere with sleep
Storage
- Keep tightly closed in a cool, dry place
- Keep out of reach of children
Ingredients
Active Ingredients (per 1 lozenge)
- Vitamin B12 (as hydroxocobalamin) – 1,000 mcg
- Folate – 1,360 mcg DFE (800 mcg folinic acid as calcium folinate)
Other Ingredients
- Xylitol
- Ascorbyl palmitate
- Natural cherry flavor
- Malic acid
- Silica
Free From
- Dairy
- Eggs
- Fish
- Shellfish
- Tree nuts
- Peanuts
- Wheat
- Soy
- Gluten
- GMO ingredients
- Artificial colors and flavors
Suitable For
- Vegetarians
- Vegans
- Individuals sensitive to methylated B vitamins
- Pregnancy and breastfeeding (under practitioner guidance)
- Ages 4 and up
Caution & Contraindications
Consult a Healthcare Practitioner Before Use If:
- Pregnant or breastfeeding
- Taking prescription medications
- Managing a medical condition
- Giving to children
Potential Side Effects
Some individuals may experience:
- Headaches
- Restlessness
- Insomnia
- Jitteriness
- Increased energy or overstimulation
- Mild digestive upset
Contraindication Considerations
Use caution in individuals with:
- Sensitivity to vitamin B12 or folate supplements
- Certain neurological or psychiatric conditions
- Cobalt sensitivity or allergy
- Conditions involving abnormal methylation pathways
Individuals taking medications that affect folate or B12 metabolism should consult their healthcare provider before use.

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