Dose & Administration

How to Use It

With meals: Take 1 capsule before eating or drinking anything high in histamine such as aged cheeses, wine, fermented foods, cured meats, leftovers, citrus, or overly ripe fruit. This is the most common use and where most people notice the most support.

On an empty stomach: This is the one most people miss and is actually quite a genius trick. Your gut bacteria and your gut’s immune system also produce histamine. If you have dysbiosis, SIBO, or an overactive gut immune response, try taking 1 capsule on an empty stomach. If you feel better within 30 minutes, that tells you your microbiome or gut immune system is producing excess histamine. Continue using it this way as needed.

For children: Ages 4 and up. Open the capsule and sprinkle on a bite of applesauce if they can’t swallow it.

During pregnancy: With your healthcare professional’s approval. Your placenta produces massive amounts of DAO but not until the 2nd trimester, which is exactly when most morning sickness eases. Supporting healthy histamine levels during the 1st trimester may support comfort.

While breastfeeding: Histamine from your gut absorbs into breast milk. Infant colic is associated with higher histamine levels in breast milk. Supporting your own histamine balance may support comfortable feeding for your baby.