Caution & Contraindications

Important Warnings

• Dietary supplements should not replace a balanced diet and healthy lifestyle.
• Use only as directed.
• Consult a healthcare practitioner if symptoms persist or worsen.

Consult a Healthcare Practitioner Before Use If:

• Pregnant or breastfeeding
• Taking prescription medications
• Have significant gastrointestinal disease
• Have chronic medical conditions requiring supervision
• Following a medically supervised treatment plan

Potential Side Effects

Butyrate is generally well tolerated; however, some individuals may experience:

• Temporary bloating
• Mild digestive changes
• Increased bowel activity
• Mild abdominal discomfort during initial use

These effects are typically temporary as the microbiome adapts.

Contraindication Considerations

Use caution in individuals with:

• Known sensitivity to any ingredient in the formulation
• Conditions requiring strict sodium management (when using Sodium Butyrate)
• Conditions requiring mineral intake monitoring (when using Calcium/Magnesium Butyrate)

Additional Notes

• Butyrate is a naturally occurring short-chain fatty acid produced by beneficial gut bacteria from dietary fibre fermentation.
• It serves as the preferred energy source for colonocytes (cells lining the colon), helping support intestinal barrier function and nutrient absorption.
• Research suggests butyrate may support healthy inflammatory responses, gut-brain communication, immune regulation, and microbiome diversity.
• Frequently used in practitioner protocols for intestinal permeability (“leaky gut”), IBS-type symptoms, microbiome restoration, digestive support, post-antibiotic recovery, and overall gastrointestinal health.